Acetonitrile
CAS 75-05-8C2H3N41.05 g/mol
Acetonitrile is a nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group. It has a role as a polar aprotic solvent and an EC 3.5.1.4 (amidase) inhibitor. It is a volatile organic compound and an aliphatic nitrile.
IUPAC: acetonitrile
PubChem
Physical & Chemical Properties
| Melting Point | -49 °F (NTP, 1992) |
| Boiling Point | 178.9 °F at 760 mmHg (NTP, 1992) |
| Density | 0.787 at 68 °F (USCG, 1999) - Less dense than water; will float |
| Solubility | greater than or equal to 100 mg/mL at 72.5 °F (NTP, 1992) |
| Flash Point | 42 °F (NTP, 1992) |
| Vapor Pressure | 73 mmHg at 68 °F (NTP, 1992) |
| Appearance | Acetonitrile appears as a colorless limpid liquid with an aromatic odor. Flash point 42 °F. Density 0.783 g / cm3. Toxic by skin absorption. Less dense than water. Vapors are denser than air. |
Data: PubChem · Last updated: 4/20/2026
GHS Classification
No GHS classification data available.
Classification data is sourced from ECHA.
Regulatory Compliance
TSCA
Listed
note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory
View sourceGlobal Trade Intelligence
No trade flow data available for this chemical.
HS Code(s): 2926
Data: UN Comtrade
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