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N,N-Dimethylformamide

CAS 68-12-2C3H7NO73.09 g/mol

N,N-dimethylformamide is a member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups. It has a role as a geroprotector, a polar aprotic solvent and a hepatotoxic agent. It is a volatile organic compound and a member of formamides. It is functionally related to a formamide.

IUPAC: N,N-dimethylformamide

N,N-Dimethylformamide molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point-78 °F (NTP, 1992)
Boiling Point300 to 313 °F at 760 mmHg (NTP, 1992)
Density0.95 at 68 °F (USCG, 1999) - Less dense than water; will float
Solubilitygreater than or equal to 100 mg/mL at 72 °F (NTP, 1992)
Flash Point153 °F (NTP, 1992)
Vapor Pressure3.7 mmHg at 77 °F ; 2.7 mmHg at 68 °F (NTP, 1992)
pHpH = 6.7 (0.5 molar solution in water)
AppearanceN,n-dimethylformamide appears as a water-white liquid with a faint fishy odor. Flash point 136 °F. Slightly less dense than water. Vapors heavier than air. Toxic by inhalation or skin absorption. May irritate eyes.

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Not Listed

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HS Code(s): 2924

Data: UN Comtrade

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