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Dimethyl sulfoxide

CAS 67-68-5C2H6OS78.14 g/mol

Dimethyl sulfoxide is a 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. It has a role as a geroprotector, an alkylating agent, a non-narcotic analgesic, a MRI contrast agent, a polar aprotic solvent, a radical scavenger, an antidote and an Escherichia coli metabolite. It is a volatile organic compound and a sulfoxide.

IUPAC: methylsulfinylmethane

Dimethyl sulfoxide molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point65.3 °F (NTP, 1992)
Boiling Point372 °F at 760 mmHg (NTP, 1992)
Density1.101 at 68 °F (USCG, 1999) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Flash Point203 °F (NTP, 1992)
Vapor Pressure0.42 mmHg at 68 °F (NTP, 1992)
AppearanceDimethyl sulfoxide appears as a clear liquid, essentially odorless. Closed cup flash point 192 °F. Vapors are heavier than air. Contact with the skin may cause stinging and burning and lead to an odor of garlic on the breath. An excellent solvent that can transport toxic solutes through the skin. High vapor concentrations may cause headache, dizziness, and sedation.

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Not Listed

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No trade flow data available for this chemical.

HS Code(s): 2930

Data: UN Comtrade

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