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Mannitol

CAS 69-65-8C6H14O6182.17 g/mol

D-mannitol is the D-enantiomer of mannitol. It has a role as a member of compatible osmolytes, a metabolite, an antiglaucoma drug, an osmotic diuretic, a sweetening agent, an allergen, a hapten, an Escherichia coli metabolite, a food anticaking agent, a food stabiliser, a food humectant, a food thickening agent and a food bulking agent.

IUPAC: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

Mannitol molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point331 to 334 °F (NTP, 1992)
Boiling Point563 °F at 3.5 mmHg (NTP, 1992)
Density1.489 at 68 °F (NTP, 1992) - Denser than water; will sink
Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Flash Pointgreater than 300 °F (NTP, 1992)
AppearanceD-mannitol appears as odorless white crystalline powder or free-flowing granules. Sweet taste. (NTP, 1992)

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Not Listed

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No trade flow data available for this chemical.

HS Code(s): 2905

Data: UN Comtrade

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