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Chloroform

CAS 67-66-3CHCl3119.37 g/mol

Chloroform is a one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines. It has a role as a central nervous system drug, an inhalation anaesthetic, a non-polar solvent, a carcinogenic agent and a refrigerant. It is a member of chloromethanes and a one-carbon compound.

IUPAC: chloroform

Chloroform molecular structure

PubChem

Physical & Chemical Properties

Physical and chemical properties
Melting Point-82.3 °F (EPA, 1998)
Boiling Point143 °F at 760 mmHg (EPA, 1998)
Density1.4832 at 68 °F (EPA, 1998) - Denser than water; will sink
Solubilityless than 1 mg/mL at 66 °F (NTP, 1992)
Flash PointNone (EPA, 1998)
Vapor Pressure100 mmHg at 50.72 °F (EPA, 1998)
AppearanceChloroform appears as a clear colorless liquid with a characteristic odor. Denser (12.3 lb / gal) than water and slightly soluble in water. Hence sinks in water. Nonflammable under most conditions, but burns under extreme conditions. May cause illness by inhalation, skin absorption or ingestion. Used as a solvent, to make other chemicals, as a fumigant.

Data: PubChem · Last updated: 4/20/2026

GHS Classification

No GHS classification data available.

Classification data is sourced from ECHA.

Regulatory Compliance

TSCA

Listed

note: Status based on EPA TSCA Active Inventory · inventory name: TSCA Chemical Substance Inventory

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SVHC

Not Listed

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FDA GRAS

Not Listed

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HS Code(s): 2903

Data: UN Comtrade

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